Human Genome Charlotte NC

In 1990, researchers at Celera Genomics and at the National Human Genome Research Institute began an ambitious endeavor to sequence the entire human genome. In 2000, researchers revealed to the general public that a substantial portion of this work had been completed. This “rough draft” of the human genome is currently in fragments much like pieces of a jigsaw puzzle. Current efforts are underway to match the different pieces to complete the puzzle. Recently, Celera Genomics revealed their startling estimation of the number of human genes to be 30,000. This estimation, based on the sequence data, is substantially below previous predictions. The sequence data has led to the estimation that less than 5% of the human genome actually encodes functional proteins. Once the jigsaw puzzle is completed, the data will undoubtedly help researchers devise new diagnostics and treatments for genetic diseases.

In addition to sequencing the human genome, researchers have sequenced the genomes of Drosophila melanogaster (fruit fly), Arabidopsis thaliana (plant), Saccharomyces cerevisiae (budding yeast), and C. elegans (worm). In addition, mouse, rat, and zebrafish genomes have been sequenced. Not only eukaryotic organisms are useful to the research community. The genome of Plasmodium (the organism that causes malaria) has also been sequenced. The goals of these sequencing projects are to prepare gene linkage maps and physical maps. A gene linkage map is a map that pinpoints the location of genes based on their connection to certain marker gene sequences. A physical map, in comparison, gives the actual number of bases between genes on a chromosome; therefore, it locates the gene of interest more precisely.

Ultimately, scientists hope to learn the actual names and sequences of all 3 billion nitrogenous bases in the human genome. Automation and computerization are essential tools in the sequencing, and the development of the specific technology is underway.

Cliffs Notes Online

CaroMont Health

To learn more about CaroMont Health and our healthcare team visit our website at www.caromont.org

704-834-2000
2525 Court Drive
Gastonia, NC
http://www.caromont.org/

The changes we’ve made could change your life. We know that life is a dynamic and often unpredictable journey which is why CaroMont Health in Gastonia, North Carolina has grown steadily to meet the region’s changing needs. From a small hospital that opened its doors 60 years ago, the 435-bed Gaston Memorial Hospital is now the anchor for CaroMont Health, an independent, not-for-profit health care system. Eight affiliate companies including a network of 33 primary and specialty physician offices deliver state of the art health care to the Gaston region.

The CaroMont Heart Center provides a full range of life-saving cardiac care including open heart surgery. And, the Comprehensive Cancer Center provides advanced 3-D radiation treatment planning and chemotherapy. An expansive, surgical suite offers the latest advancements such as stereotactic technology, a procedure using computer similation, microscopic surgery and x-ray images for pinpoint accuracy. A level III neonatal intensive care unit for high risk infants and a pre-adolescent psychiatric center are among the latest services aimed at improving the health status of our community.

CaroMont Health is an organization with 312 physicians and 3,400 health care professionals working to provide the finest care to those who are sick, and effective prevention strategies to those who are well. Located at 2525 Court Drive in Gastonia, N.C., CaroMont Health can be reached at 704-834-2000.


– http://www.caromont.org/
– http://www.caromont.org/